despair

despair 1

• noun [U]

a feeling of being very unhappy and without hope:
?in despair: Anne buried her head in her hands in despair


despair 2

• verb [I]

to feel that there is no hope at all:
?Don't despair - I think we can help you.
?despair of: They were beginning to despair of ever hearing from their son again.
despairing adjective